mRNA Vaccines: Revolutionizing Rapid Immunization Against Infectious Diseases mRNA Vaccines: Revolutionizing Rapid Immunization Against Infectious Diseases Introduction Traditional vaccines have protected millions for decades but often require years of development. The introduction of mRNA vaccine platforms has dramatically accelerated this timeline, enabling rapid responses to emerging infectious diseases. This review, published in Nature Reviews Drug Discovery in 2020, summarizes how mRNA vaccines function, their rapid design and production, and their success against diseases like influenza, Zika, cytomegalovirus, and COVID-19. Unlike conventional vaccines, mRNA vaccines provide cells with genetic instructions to produce harmless viral proteins. The immune system then recognizes these proteins and mounts a protective response — all without exposure to live viruses. Ba...
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